Treatment with Analgesics, Phlebotonics, Venoactive drugs and Hormone therapy may lessen discomfort and the size of the varicose veins.

Analgesics can be used to ease pain, however symptoms should not be ignored if pain reoccurs when treatment has stopped. Hormone therapy may show benefits when symptoms are cyclic. Examples of some Hormone therapy that have shown some transient pain improvement are; progestins (contraceptives, hormone replacement therapy, danazol), gonadotropin-releasing hormone (GnRH) agonists and the etonogestrel implant. There is limited data that intravenous dihydroergotamine may be effective in decreasing the size of uterine and parametrium veins and alleviating pain symptoms; use is unfortunately limited by transient efficacy and adverse side effects.⁴

Venoactive drugs, and, more specifically, the micronized purified flavonoid fraction (MPFF*), have been investigated for the treatment of PCS.^9,10. These medications have a protective and tonic effect on the venous and capillary wall, which increases venous tone, improves lymphatic drainage, and reduces capillary hyperpermeability resulting in a reduction in venous stasis. MPFF has been widely studied in the treatment of patients with symptomatic chronic venous disease.⁵

Medical management of PCS can prove to be helpful, however, there is insufficient evidence regarding their long-term effectiveness or side -effects in controlling debilitating symptoms.⁵

Please speak with your doctor as treatments should be adapted based on symptoms, your medical history and your individual needs.